domingo, noviembre 12, 2006

Motivational Interviewing Improves Antiretroviral Adherence

Motivational Interviewing Improves Antiretroviral Adherence

CME
Advances in the Treatment of Patients Coinfected With HIV and HBV or HCV Coinfection with HIV and HBV or HCV poses challenges in the treatment of each disease. Drs. Vincent Soriano and Douglas Dieterich review the latest data and strategies for treatment.

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NEW YORK (Reuters Health) Jun 12 - A motivational interviewing-based intervention improves adherence to antiretroviral therapy in HIV patients, according to a report in the May Journal of Acquired Immune Deficiency Syndromes.

Motivational interviewing is an effective, client-centered counseling approach, the authors explain. It involves focusing on concerns raised by the patient, with developing medication self-management skills.

Dr. Carol E. Golin and colleagues from University of North Carolina at Chapel Hill, North Carolina developed the Participating and Communicating Together (PACT) motivational interviewing program and tested its effect on objectively measured antiretroviral adherence compared with an informational control program.

The study involved 140 adult HIV-infected patients who were either failing or newly initiating an antiretroviral therapy regimen. Mean adherence in the intervention group improved by 4.5% compared with a 3.83% decrease in the control group, the authors report.

Weekly adherence over time also increased in the intervention group and decreased in the control group, the results indicate.

The intervention group was 2.75 times more likely than the control group to achieve more than 95% adherence, the researchers note.

At the end of the study, significantly more patients in the intervention group (92%) than in the control group (79%) felt that their antiretroviral medications were definitely worth taking, the report indicates.

The investigators say that there was no statistically significant difference in change in viral load between the two groups.

"Although not definitive," the authors conclude, "this study provides some evidence that motivational interviewing offers an effective approach to improving adherence."

J Acquir Immune Defic Syndr 2006;42:42-51.

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